What You Need to Know About Total Bilirubin
Have you ever noticed the term total bilirubin on your blood test and wondered what it means? You’re not alone. Most people skip over it unless it’s marked high or low.
But that small number can reveal a lot about what’s happening inside your body. When your doctor mentions liver function, jaundice, or unusual test results, it suddenly becomes important.
Let’s break down what total bilirubin is, why it matters, and what it says about your health.
What is Total Bilirubin?
Total bilirubin is a substance your body makes when it breaks down old red blood cells. It’s a natural process. As red blood cells age and die, your liver helps recycle them. During that recycling, bilirubin is formed.
Think of it this way…your blood cells are delivery trucks that only operate for about 120 days. After that, your body needs to clear them out and clean up. Bilirubin is part of that clean-up crew. Your liver collects it, processes it, and eventually pushes it out of your body through your stool.
So why should we care about bilirubin? Because it gives your liver a chance to tell us how it’s doing. If your bilirubin levels are off, your liver could be having a hard time processing waste, or something else could be going on with your blood or gallbladder.
How is Total Bilirubin Tested?
Getting your total bilirubin tested is usually straightforward. It’s done with a simple blood draw, often part of a standard liver function panel or a comprehensive metabolic panel.
Your doctor might order it during a routine check-up or if you’ve been having symptoms like fatigue, yellowing skin, or dark urine.
You may hear the term ‘bilirubin blood test’ used as part of a broader lab panel. Here’s a quick look at how it works:
Test Method | Description |
The most common and accurate method. Measures both direct and indirect bilirubin. | |
Urine Test | Sometimes used, but less detailed for bilirubin specifically. |
At-Home Kits | These exist, but accuracy and reliability can vary. Always confirm with a lab-based test. |
In many cases, you’ll be asked to fast for at least 4 to 8 hours before the test. This just means avoiding food and drinks (except water) to ensure that your results aren’t skewed.
Medications may also affect results, so your doctor might tell you to pause some of them, but always ask before stopping anything.
Most people get this test done at a doctor’s office, hospital, or diagnostic lab. Some private companies now offer at-home blood tests, but they’re best used with medical guidance.
Why is Total Bilirubin Tested?
There’s no single reason for this test; it can reveal several things to doctors, depending on your health history, symptoms, or other lab results. One of the most common reasons is to check liver function.
You might need this test if you’re showing symptoms of jaundice, like:
- Yellowing skin or eyes
- Dark-colored urine
- Light-colored stools
- Itchy skin
- Fatigue
Doctors also use it when monitoring chronic liver conditions like hepatitis or cirrhosis. It can help detect bile duct issues, such as blockages, and uncover causes of unexplained fatigue or anemia.
Since bilirubin also plays a role in the breakdown of red blood cells, this test can provide insights into blood disorders as well.

What Do the Results Mean?
Now here’s where most people get stuck reading the results.
Normal Bilirubin Range
Most labs consider a normal range to be around 0.1 to 1.2 mg/dL. But don’t panic if you’re slightly outside that.
Different labs use slightly different reference points, and what’s normal for one person might be different for another.
If Levels Are High
High bilirubin levels can mean a few different things. Here’s a breakdown of possible causes:
Possible Cause | What It Could Mean |
Liver damage (e.g. hepatitis) | Liver may not be processing bilirubin well |
Bile duct blockage | Bilirubin can’t leave the liver properly |
Hemolysis | Blood cells are breaking down too quickly |
Genetic conditions | Such as Gilbert’s syndrome |
Medication effects | Certain drugs affect liver enzyme function |
Signs to watch for:
- Yellow eyes or skin
- Itching
- Pain under your right ribs
- Feeling tired or foggy
If Levels Are Low
It’s less common, but low levels can sometimes show up. While it’s not usually a red flag, very low bilirubin might be related to overhydration or sometimes errors in testing.
Most of the time, it doesn’t signal a serious issue, but your doctor will help interpret it in context.
What Affects Total Bilirubin?
This is where lifestyle and day-to-day habits come into play.
Lifestyle Factors:
- Alcohol: Heavy drinking can inflame the liver and disrupt how bilirubin is processed.
- Diet: Diets high in processed food or sugar can wear down liver function.
- Dehydration: Not drinking enough water makes bilirubin more concentrated in the blood.
- Stress and poor sleep: These don’t affect bilirubin directly, but can lead to other health problems that do.
Medical Factors:
- Liver diseases (like hepatitis or cirrhosis)
- Genetic conditions
- Side effects of medications (like antibiotics, birth control pills, or NSAIDs)
Temporary Factors:
- Fasting or crash dieting
- Strenuous exercise
- Acute illness, like the flu
Think of bilirubin levels as a sensitive mirror. They reflect both long-term patterns and short-term events in your body.
How to Improve or Maintain Healthy Levels
If your levels are off, it doesn’t always mean something serious is wrong, but it does mean your body is asking for attention. Here’s what you can do, depending on whether they’re too high or unusually low.
If Levels Are High
- Eat liver-friendly foods:
- Leafy greens
- Cruciferous vegetables (broccoli, Brussels sprouts)
- Beets
- Fresh fruits
- Cut back on:
- Fried foods
- Alcohol
Excess sugar
- Stay hydrated.
- Move your body: gentle, regular exercise helps circulation and liver function.
- Check your medications: some may be affecting your liver. Always ask before making changes.
If Levels Are Low
Low total bilirubin doesn’t usually require treatment. But if your doctor sees it alongside other symptoms, they may look deeper. Eating a balanced diet and keeping your hydration in check is often enough.
When to Talk to Your Doctor
Pay attention to your body. If you notice symptoms of jaundice, fatigue, dark urine, or pain in your upper right abdomen, bring it up. Even if you feel fine, having test results out of range, especially if it keeps happening is worth a second look.
And don’t get too focused on one number. Your doctor will look at your bilirubin alongside other markers like liver enzymes (ALT and AST), proteins, and red blood cell counts. Together, they tell a much bigger story.
Why Lifespire Cares About Total Bilirubin
At Lifespire, we pay close attention to markers like total bilirubin because they help us see the full picture of your health. Even small changes can hint at how your liver and blood are functioning long before symptoms appear.
This isn’t just a lab number. It’s part of your story. By tracking it, we can guide you toward better choices, earlier care, and a deeper understanding of your body. It’s one way we help you stay informed, supported, and ahead of the curve.

Total bilirubin might not be something you’ve thought much about, but it tells a meaningful story about your body’s balance. When it’s in range, your liver and blood are likely doing their job. When it’s not, it’s a sign to pay attention.
Staying informed helps you take small, steady steps toward better health. Even one number can point you in the right direction.
For deeper insight and personalized support, visit our Longevity Program and take control of your health journey.